DNA Damage


DNA is under constant attack from reactive
chemicals and natural background radiation. Free radicals are the byproducts of
normal metabolism in human cells. Seen here as bright particles, they sometimes
react with DNA and cause chemical changes. Radiation can also affect DNA; for example, ultraviolet light from the sun can
cause harmful chemical changes in the DNA of skin. These changes can lead to kinks in the
DNA that prevent genes from being correctly read, or deletions that
alter the type of protein produced. Thanks to constant biochemical repair work, most
mutations are corrected before they have any effect. But in rare cases, mutations can accumulate,
and this can give rise to diseases such as cancer.

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