GTR: The All GTR Search Function


This video introduces the new All GTR search,
which we designed based on feedback from GTR users like you. Starting on the GTR home page, you may notice
that the default search tab is now All GTR instead of the Conditions tab. The term you
enter will be searched across all domains of GTR content – Tests, Conditions, Genes,
and Laboratories. All GTR supports searches for tests based
on combinations of conditions, genes, or Labs. While this demonstration focuses on the All
GTR search, you can still select another tab for a more limited search. I’ll start by searching for the condition
name Ehlers. As you type in your term, the autocomplete dictionary shows several potential
matches. You can select a specific term in the list, which would take you directly to
a page for that condition; it does not execute a search. Instead of selecting a specific
term, I’ll just press the enter key. GTR interpreted my search term to be a condition,
so results are displayed for the conditions tab, but I have the option to see results
for Tests, Genes, or Labs. Let’s take a closer look at the results
for conditions. Genetic conditions typically are known by a variety of names. The primary
condition term is shown in the left-hand column, and a list of synonyms is in the right-hand
column. Looking at the first result, Ehlers-Danlos
syndrome type 4, also known by the disease acronym EDS4, I see links to the GTR page
for Tests and for Genes for EDS4, and also a link to the GeneReviews article for this
condition. The condition name itself is also hyperlinked,
and that takes you directly to the condition-specific GTR page with its wealth of information. Let’s say I want tests that target either
of two conditions, EDS type 4 or EDS type 1. I’ll check the boxes to the left of each
condition name, and I now see the link, Show tests that evaluate any of the checked conditions.
Before I click that link, note the total count of tests for the term Ehlers, 224, today. Now, after clicking the Show tests link, I’m
taken to the All GTR Tests tab; and I see that these two conditions have 84 tests. Counts
for the other tabs have been updated as well. I see a familiar set of filters on the left,
and I want to point out now some new features on this Tests page. You see columns for the number of conditions
and for test targets, such as genes. These numbers give you a quick idea of whether the
test is a complex panel or a single gene test. By the way, you can use the Advanced search
function found on the GTR home page to select tests based on the number of genes they analyze,
or specify which genes and conditions you want to test. At the end of this video will
be a link to the Advanced Search video. Clicking on either of these numbers pops up
a list of these conditions and test targets, as well as the methodology. You can also navigate
to the test’s full record via the See Test Details button. 84 tests is still a fairly long list, so another
strategy is to move to the Laboratories tab. I’ll then select labs in Massachusetts, and
then check both resulting labs and follow the new link that starts, Limit your search
to include… The resulting page lists four tests provided by Massachusetts labs for my
two original conditions, EDS4 and EDS1. I now want to demonstrate how to search by
gene symbol, but first, notice that I can start a new search of All GTR while on this
page. I’ll delete the existing search term, and since EDS is associated with several collagen
genes that begin with ‘C-O-L’, I’ll type that and, avoiding a specific gene symbol
in the list, hit the enter key to run the search. I’m shown a list of alphabetized results,
not all of which begin with c-o-l. That is because GTR also searches alternate gene symbols.
Hovering your mouse over a gene symbol reveals the gene’s full name.
Clicking on it would take you to the GTR page about that gene. In addition to a column of conditions associated
with each gene, there is a link to Tests below each gene symbol. As with the conditions tab, selecting two
or more boxes to the left of the gene symbols activates a link for tests that evaluates
any of the checked genes. For my final search I want to point out that
you can search All GTR for a variety of terms, such as a unique test name, or the name of
a laboratory staff member. For example, searching on ‘Tanner’ gives this condition result
because there is a citation by Tanner in the record, but if I am looking for a lab director
name, then I’d click on the Laboratories tab. Each of these labs has a staff member with
the name Tanner. That’s it for this demo. Don’t forget, rather
than searching All GTR, you can always limit your search by selecting a category in the
drop-down menu. And if you ever get stuck, go back to the GTR home page and follow this
link, How to use GTR – that has many more useful tips. We do value your feedback and will keep improving
GTR based on what you say. So please keep the comments, kudos and suggestions coming
by using this link, Contact us and provide feedback. Thank you for your interest in the
NIH Genetic Testing Registry. You can now click on this note to open the
video about using the Advanced Search function.

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