Susan Taylor (UCSD) Part 1: Protein Phosphorylation in Biology September 10, 2019 Tags:and, biology, iBioSeminars, protein kinase, protein phosphoylation, Susan Taylor, that, the Related Posts Brian Barczyk & Why Spider Ball Pythons are Terrible RNA Transposons Taíno Symposium – Session 2 – Jada Benn Torres About The Author John Henderson 23 Comments comeoriginal33 thank you! i found this very informative and helpful! 🙂 March 8, 2011 Reply cecilia rosa Thank You so much!!! August 29, 2011 Reply funnychoob This video is Great!! Thank you so much for this piece of information! January 28, 2012 Reply electrolyte1000 Funny she said an average 70 kDa person turns over 40 kg of ATP per day March 30, 2012 Reply 뉴욕아줌마 NY ajumma Fantastic, thank you. April 15, 2012 Reply zaid zainuddin great video! zillions of thumbs ups! August 16, 2012 Reply kate winslet IκBs are a family of related proteins that have an N-terminal regulatory domain, followed by six or more ankyrin repeats and a PEST domain near their C terminus. IκBα is the best-studied and major IκB protein. December 14, 2012 Reply Mehrdad Rostami Thank you December 31, 2012 Reply Abi and Eva I found it great but couldn't focus much because of so much swaying back and forth. August 15, 2013 Reply ChrisOfTheInternets Very helpful video! November 18, 2013 Reply ALOK PATRA Thanks Susan! December 31, 2013 Reply Tom Schneider 4:07 the year should be 1987. See http://www.ncbi.nlm.nih.gov/pubmed/2434996 February 5, 2014 Reply Rodrigo Marcondes Thanks for the class!!! April 7, 2014 Reply jordan walter Awesome, great content and context! August 9, 2014 Reply lizichell2 this is fabulously interesting = 7 likes October 1, 2014 Reply ALBERTO VALSANIA PECCATO CHE NON CONOSCO L'INGLESE December 17, 2015 Reply Richard de Goeij-deHaas Great video lecture!!. Performing phosphoproteomics research on biopsy material from cancer patients. Its good to back to the basics for a good understanding.Especially the historic context is very interesting.Has someone ever written a book about the history of molecular biology ?? September 3, 2016 Reply T.Theodorus Ibrahim 80 dalton mass for phosphate group, not 80 kilodaltons 🙂 September 17, 2016 Reply Caroline Green #Kinases transfer the γ-phosphate of ATP to other biological molecules, serving as chemical messengers that make the tight regulation of cell-signaling pathways possible. For example, non-receptor tyrosine kinases are found in the cytoplasm (not membrane-bound) and transfer the γ-phosphate of ATP to tyrosine residues of other proteins, often turning these proteins “on” or “off” in the context of their respective signaling pathway. This notion of “on” or “off” can be useful to holistically conceptualize these pathways but is a gross oversimplification; in reality, many of these enzymes are multi-domain proteins that can exist in multiple conformational states, participate in multiple protein-protein interactions, and experience a gradient of variable activity levels depending on these states. The molecular mechanisms that govern the activity of these kinases is extraordinarily complex, and though much has been discovered in recent years, much remains to be understood, especially for the Tec family of non-receptor tyrosine kinases. January 16, 2017 Reply akrrrs 1 This is brilliant. Thanks Prof. Taylor December 15, 2017 Reply Michael Harris Thanks, great video June 12, 2018 Reply Anna Kaniauskene Extremely interesting and enlightening Thank you. June 13, 2018 Reply Robert Huang these lectures are awesome. This whole channel is awesome. Thanks for the content! January 25, 2019 Reply Add a Comment Cancel reply Your email address will not be published. Required fields are marked *Comment Save my name, email, and website in this browser for the next time I comment.